We study the properties of solutions of quadratic programs with linear equality constraints whose parameters are estimated from data in the high-dimensional setting where $p$, the number of variables in the problem, is of the same order of magnitude as n, the number of observations used to estimate the parameters. The Markowitz problem in Finance is a subcase of our study. Assuming normality and independence of the observations we relate the efficient frontier computed empirically to the ``true" efficient frontier. Our computations show that there is a separation of the errors induced by estimating the mean of the observations and estimating the covariance matrix. In particular, the price paid for estimating the covariance matrix is an underestimation of the variance by a factor roughly equal to 1-p/n. Therefore the risk of the optimal population solution is underestimated when we estimate it by solving a similar quadratic program with estimated parameters. We also characterize the statistical behavior of linear functionals of the empirical optimal vector and show that they are biased estimators of the corresponding population quantities. We investigate the robustness of our Gaussian results by extending the study to certain elliptical models and models where our $n$ observations are correlated (in ``time"). We show a lack of robustness of the Gaussian results, but are still able to get results concerning first order properties of the quantities of interest, even in the case of relatively heavy-tailed data (we require two moments). Risk underestimation is still present in the elliptical case and more pronounced that in the Gaussian case. We discuss properties of the non-parametric and parametric bootstrap in this context. We show several results, including the interesting fact that standard applications of the bootstrap generally yields inconsistent estimates of bias. Finally, we propose some strategies to correct these problems and practically validate them in some simulations. In all the paper, we will assume that p, n and n-p tend to infinity, and p




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