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These interviews with Keiichi Itakura, a professor in the Division of Molecular Biology at the Beckman Research Institute of the City of Hope Medical Center in southern California, are included in the oral history series on Genentech because of his seminal contributions to Genentech’s three earliest research projects. At a time in the 1970s when scientists with the capacity to synthesize DNA by entirely chemical means were few and far between, Itakura and Arthur Riggs, his colleague at City of Hope, conceived of combining DNA synthesis and recombinant DNA with the aim of constructing and reproducing genes that would code for useful proteins.

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