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Pennica discusses her work at Genentech, especially the cloning of t-PA, the "clot buster" tissue plasminogen activator. She also discusses work her other research, including work on urokinase, tumor necrosis factor, p53, uromodulin and cardiotropin. Supplementary material: interviewee's curriculum vitae, copy of letter regarding Pennica's Inventor of the Year award, and a photo.

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