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Graduate students, postdocs, staff and observers of the Melvin Calvin bio-organic chemistry group at UC Berkeley from 1945-1963 are interviewed on the methods, management, community and culture of the Calvin lab; the Donner Laboratory-based group's work on organic reaction mechanisms and radioactive synthesis; work on photosynthesis in the Old Radiation Laboratory (ORL); years after 1959 in the Life Sciences Building, and the move to the Round House (Melvin Calvin Laboratory; recollections of Sam Ruben, Martin Kamen, UC Radiation Laboratory, E.O. and John Lawrence.

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