James Born was a lawyer turned physician who worked as a medical researcher and director of the Donner Laboratory. He was born and raised in Ann Arbor, Michigan, and graduated law school in 1940. He then decided to switch careers, and went to medical school at the University of Wisconsin. He moved to California and began working at the Donner Laboratory, where he studies radioactive medicine. In 1970 he was appointed director of the Donner Laboratory, and remained in the position until 1975. In this interview, Born discusses all this and: influences in his career change to medicine; marriage to Jean Louise Chapman; radioactive techniques developed for specific diseases; funding; the omnitron, bevelac, and other tools; recollections of William Goodricke Donald and John J. Lawrence; the medical program at UC Berkeley; and collaborations among Lawrence Berkeley Laboratories, Donner Laboratory, and Radiation Laboratory.