Family background; education at M.I.T., and PhD from Columbia University, 1949; Stanford University: professor of mathematics and statistics 1947-1963, Dean, Graduate Division 1959-1963, development of statistics department and laboratory, and government-industry relations; Chancellor, City University of New York, 1963-1971: establishment of new colleges, graduate center, handling race relations, open admissions, city and state politics; UC Berkeley Chancellor 1971-1980: Master Plan; report, Berkeley in a Steady State; academic quality and fiscal stringencies; Bakke case, issues of access and discrimination; intercollegiate athletics; ROTC; craftworkers' strike; government regulations; moving fund raising to Chancellor's Office; role of professional schools; faculty union; ventures in health and medical science; eliminating departments; Strawberry Creek College; Experimental College Program; relations with alumni, other East Bay colleges and universities, faculty, students, University constituents, Regents, City of Berkeley; other Berkeley reminiscences; University of Maryland 1981-1986, and government posts.