Alexander Grendon was a radiophysicist and biophysicist who was involved in the first research projects of the Donner laboratory, now the Lawrence Berkeley National Laboratory. Grendon was born in New York in 1899 and earned his Bachelor of Science degree from Columbia University in 1919. He was a specialist in radar and radiological warfare for the US Army from 1940–1954, during which time he trained as a radiological defense engineer. After retiring from the Army as a Colonel, he became a research assistant at the Donner Laboratory at UC Berkeley, and later coordinated atomic energy development and safety for the State of California. In this interview, Grendon discusses his work at the Donner Laboratory with Dr. Hardin Jones, a professor of Medical Physics and Physiology; radiation safety standards; debates with Edward Teller over the safety of radiological technology; and the creation of the UC Berkeley Institute of Human Development.