Modern applications for high speed optical links demand low noise as a fundamental constraint. Much prior work exists in terms of low noise optimization, with various different techniques and architecture proposed, but few are generalizable across process and are comprehensive enough for other designers to use. This work investigates fundamental techniques at both an architectural level through equalization and system-wide co-optimzation and low-level component sizing techniques achieved through automated design script also covering layout and schematic generation. The result is a true push-button flow interfacing with Berkeley Analog Generator that takes in a generic set of desired system specifications and produces a corresponding layout and schematic of a satisfactory system. The proposed methodology, techniques, design scripts and resultant push-button flow are validated across multiple design points with various photodiode models by taping out three macro designs in a 45nm SOI process.